Author: Tessa Bouwmeester

Development of a High-Throughput Heart-on-a-Chip Platform using Pipetting Robots.  A Heart-on-a-Chip is a microfluidic chip reproducing the organ’s function using heart muscle cells cultured inside the chip chamber. This technique is a promising tool for drug development and a cost-efficient alternative for the ethically questionable animal models.  In order to push this technique towards to…

Electrical stimulation of Cardiomyocytes in a Heart-on-a-Chip. Atrial Fibrillation (AF) is a serious health status affecting 33 million worldwide. The drug development for AF is cost intensive and a time-consuming process. Organ-on-Chip technology has the potential to revolutionize drug development. While conventional processes involve animal testing, this number can be reduced significantly by using human…

An osteoblast/osteoclast co-culture model to study menopause related osteoporosis. Menopause marks the final menstrual period in a woman’s life. In the period preceding menopause, called perimenopause, a shift in hormonal balance occurs. While some women go through this period uneventfully, others experience negative consequences that affect their physical health and workability. One of the physical…